Biology of Sport
pISSN 0860-021X    eISSN 2083-1862
Archival Issues
Volume 34, 2017
Volume 33, 2016
Volume 32, 2015
Volume 31, 2014
Volume 30, 2013
Volume 29, 2012
Volume 28, 2011
Volume 27, 2010
Volume 26, 2009
Volume 25, 2008
Volume 24, 2007
Volume 23, 2006
Volume 22, 2005
Volume 21, 2004
Volume 20, 2003
Archival Issues 1984-1998
Search
Newsletter
Information for Authors
Special Information
 » 
Journal Abstract
 
HIGH-INTENSITY EXERCISE TRAINING INDUCES MORPHOLOGICAL AND BIOCHEMICAL CHANGES IN SKELETAL MUSCLES
Luca Toti, Alessia Bartalucci, Michela Ferrucci, Federica Fulceri, Gloria Lazzeri, Paola Lenzi, Paola Soldani, Antonio La Torre, Marco Gesi
Biol Sport 2013; 30(4):301-309
ICID: 1077557
Article type: Original article
IC™ Value: 10.00
Abstract provided by Publisher
 
In the present study we investigated the effect of two different exercise protocols on fibre composition and metabolism of two specific muscles of mice: the quadriceps and the gastrocnemius. Mice were run daily on a motorized treadmill, at a velocity corresponding to 60% or 90% of the maximal running velocity. Blood lactate and body weight were measured during exercise training. We found that at the end of training the body weight significantly increased in high-intensity exercise mice compared to the control group (P=0.0268), whereas it decreased in low-intensity exercise mice compared to controls (P=0.30). In contrast, the food intake was greater in both trained mice compared to controls (P<0.0001 and P<0.0001 for low-intensity and high-intensity exercise mice, respectively). These effects were accompanied by a progressive reduction in blood lactate levels at the end of training in both the exercised mice compared with controls (P=0.03 and P<0.0001 for low-intensity and high-intensity exercise mice, respectively); in particular, blood lactate levels after high-intensity exercise were significantly lower than those measured in low-intensity exercise mice (P=0.0044). Immunoblotting analysis demonstrated that high-intensity exercise training produced a significant increase in the expression of mitochondrial enzymes contained within gastrocnemius and quadriceps muscles. These changes were associated with an increase in the amount of slow fibres in both these muscles of high-intensity exercise mice, as revealed by the counts of slow fibres stained with specific antibodies (P<0.0001 for the gastrocnemius; P=0.0002 for the quadriceps). Our results demonstrate that high-intensity exercise, in addition to metabolic changes consisting of a decrease in blood lactate and body weight, induces an increase in the mitochondrial enzymes and slow fibres in different skeletal muscles of mice, which indicates an exercise-induced increase in the aerobic metabolism.

ICID 1077557

DOI 10.5604/20831862.1077557
PMID PMC3944543 - click here to show this article in PubMed
 
FULL TEXT 920 KB


Related articles
  • in IndexCopernicus™
         electron microscopy [14 related records]
         morphology [29 related records]
         training [1 related records]
         skeletal muscles [0 related records]

  • Related articlesin PubMed database
  • in PubMed database [ related records]


  •  

    Copyright © Biology of Sport  2017
    Page created by Index Copernicus Ltd. All Rights reserved.