Comparison of the effects of continuous versus intermittent exercises on the activity of superoxide dismutase in rat tissues A Frankiewicz-Jóźko, J Faff Biol Sport 2005; 22(4):341-352 ICID: 891455
Article type: Original article
IC™ Value: 10.26
Abstract provided by Publisher
The aim of the present study was to investigate the effects of adaptation to continuous as compared to intermittent endurance exercises performed with low and high intensities, respectively, on the activity of superoxide dismutase in the mitochondrial (MnSOD) and post-mitochondrial (CuZnSOD) fractions of the rat liver, heart, and red (RG) and white (WG) portions of the gastrocnemius muscle. The adaptation protocol consisted of running daily for four weeks, five days per week, the 600 meter-distance on a mechanical treadmill slanted at 15°, at the speed of 10 m/min (EE) or of 30 m/min with a four-minute-break every two minutes (IE). The results demonstrate that in the RG the activity of MnSOD increased after the intermittent exercises p<0.001), whereas that of CuZnSOD raised following .both types of the exercises (p<0.05). Concurrently, neither intermittent nor continuous exercises triggered any changes in the CuZnSOD or MnSOD activities in the WG. After the continuous exercises, the elevated activities of MnSOD (p<0.001) and CuZnSOD (p<0.05) were found in the liver and heart, respectively. The MnSOD activity in the heart muscle was reduced after both the IE and EE (p<0.05). The obtained results suggest that adaptation to intermittent versus continuous endurance exercises differently affects the activity of superoxide dismutase.