Effect of eccentric and concentric exercise on plasma creatine kinase (CK) and lactate dehydrogenase (LDH) activity in healthy adults S Poprzęcki, A Staszkiewicz, E Hübner-Woźniak Biol Sport 2004; 21(2):193-203 ICID: 891899
Article type: Original article
IC™ Value: 10.26
Abstract provided by Publisher
The aim of the research was to determine the influence of concentric and eccentric muscular work on plasma creatine kinase (CK) and lactate dehydrogenase (LDH) activity during a graded exercise protocol. The research material included 10 students of physical education. All of them performed the treadmill exercise protocol twice, under different conditions (test I – uphill run- concentric work, test II – downhill run – eccentric work). Oxygen uptake was registered during both tests. Blood samples were taken from the antecubital vein before, during and 2, 7 and 24 h after the test. The effort with a predominance of concentric muscular work elicited a significantly (P<0.01) higher blood acidosis in comparison to the eccentric one. Both efforts caused a significant (P<0.05) increase in plasma CK and LDH activity. After 24 h of rest CK activity continued to rise while plasma LDH activity returned to pre exercise value. After 7 and 24 h of recovery plasma CK activity was significantly (P<0.05) higher following the eccentric form of exercise. Simultaneously, increase of CK activity during recovery after the eccentric work, pointing at the deterioration of muscle cells, was stated just after 7 h of rest. It proves proper functioning of adaptive mechanisms and that the level of CK activity in plasma immediately after effort does not reflect muscles functioning disturbances.