Biology of Sport
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Journal Abstract
 
POLYMORPHISM OF THE α-ACTN3 GENE IN INDIVIDUALS PRACTISING DIFFERENT SPORTS DISCIPLINES
J Holdys, D Stanisławski, J Kryściak, P Gronek
Biol Sport 2011; 28(2):101-106
ICID: 942738
Article type: Original article
IC™ Value: 10.06
Abstract provided by Publisher
 
In this study the R577X polymorphism of the α-actinin-3 (ACTN3) gene was analysed in relation to physical fitness measured with maximal oxygen uptake (VO2max). The studies were carried out in a group of 154 men and 85 women, students of the University of Physical Education in Poznań and professional athletes representing various sports and fitness levels. In our research physiological and molecular procedures were used, i.e. direct measurement of maximum oxygen uptake (VO2max) and R577X a-ACTN3 genotyping by PCR-RFLP. The results do not confirm some literature data concerning a statistically significant association of R577X polymorphism in the ACTN3 gene and the level of maximal oxygen uptake (VO2max). A trend was observed for higher VO2max values to be found in individuals with the XX and RX genotypes as well as the predominance of the RR genotype in the group of individuals practising speed and power disciplines.

ICID 942738

DOI 10.5604/942738
 
FULL TEXT 321 KB


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